Full vs. low-dose of direct oral anticoagulants as extended secondary prophylaxis of venous thromboembolism in the splanchnic venous thrombosis

Full vs. low-dose of direct oral anticoagulants as extended secondary prophylaxis of venous thromboembolism in the splanchnic venous thrombosis

Silvia Sorella, Mario Biglietto, Nadezda Zhdanovskaya, Manuela Merli, Alessandro Laganà, Antonio Chistolini

Department of Translational and Precision Medicine Sapienza University of Rome, Italy

Highlights

• Splanchnic venous thrombosis has a high risk of recurrence.
• An extended secondary prophylaxis with anticoagulants is needed in this setting.
• Direct oral anticoagulants may be useful in this setting.
• Low dose DOACs may be non-inferior to full-dose in the extended therapy.